Traditional Uses

• Relief of
  • Sleeplessness
  • Nervousness and
  • Edginess
    due to overwork, stress or fatigue

Mode of Action

• Contains valepotriates, and valerenic acids which have sedative and anticonvulsant activity
• Helps maintain levels of GABA (gamma-aminobutyric acid)

Drug Interactions

• May increase the effects of pentobarbital
• Do not use with sedatives, hypnotics, anesthetics and central nervous system depressants

Cautions

• Do not take if already taking sleep-inducing drugs
• May cause heartburn, upset stomach, diarrhea and allergic reactions in large doses
• May cause drowsiness. Avoid using heavy equipment or driving while using this product

Recommended Dose

• 400-800 mg at bedtime. (Dose may vary from brand to brand)

References

• Bisset, 1994; Blumenthal, 1998; Chevallier, 1996; Harris, 1985; Hoffman, 1990; Newall, 1996; Tyler, 1993; Tyler, 1994; Weiner, 1994; Wild, 1994