Traditional Uses

• Excessive mucous secretion in the upper respiratory tract
• Gastric and duodenal ulcers
• Adrenal agent
• Mild laxative

Mode of Action

• Contains Triterpene saponins (glycyrrhizin), flavonoids, coumarins, sterols and some polysaccharides.
• Glycyrrhizin has an anti-inflammatory and antiarthritic action
• Stimulates production of hormones by the adrenal glands
• Reduces the breakdown of steroids by the liver and kidneys
• Reduces stomach secretions and produces a thick protective mucus for the lining of the stomach, resulting in a useful remedy in inflammatory stomach conditions

Drug Interactions

• Potassium loss due to other drugs can be increased.
• With potassium loss, sensitivity to digitalis increases
• Reduces the absorption of ASA

Cautions

• May increase blood pressure. Not appropriate to take if there is a history of hypertension, diabetes, glaucoma, stroke, or heart disease
• Do not take if pregnant
• Do not take if anemic
• Do not take for a period longer than 4-6 weeks without medical advice
• Stop using the herb immediately if there are side effects such as headaches, bloating, or lethargy

Recommended Dose

• 1000-4000 mg once a day. (Dose may vary from brand to brand)

References

• Blumenthal, 1998; Chevallier, 1996; Elias, 1995; Lust, 1974; Nutriceutica, 1998